Which method is NOT a DNA/chromosomal level technique for genetic testing?

Which method is NOT a DNA/chromosomal level technique for genetic testing?

• A. In situ hybridization
• B. Karyotyping
• C. Disease phenotype analysis
• D. DNA sequencing

Answer: (C)

The choice referring to disease phenotype analysis is considered the correct answer because it does not involve examining DNA or chromosomes directly. Instead, this method focuses on the observable characteristics or traits expressed by an organism, which can be influenced by both genetic and environmental factors. On the other hand, in situ hybridization, karyotyping, and DNA sequencing are all techniques that specifically analyze DNA or chromosomes. In situ hybridization allows for the localization of specific DNA sequences within chromosomes or tissue sections. Karyotyping is a method used to visualize the complete set of chromosomes in an organism, which helps in identifying chromosomal abnormalities. DNA sequencing involves determining the precise order of nucleotides within a DNA molecule, providing insights into the genetic code. Thus, disease phenotype analysis stands apart as it does not directly manipulate or assess the nucleic acid level, making it the appropriate selection for this question.

The choice referring to disease phenotype analysis is considered the correct answer because it does not involve examining DNA or chromosomes directly. Instead, this method focuses on the observable characteristics or traits expressed by an organism, which can be influenced by both genetic and environmental factors.

On the other hand, in situ hybridization, karyotyping, and DNA sequencing are all techniques that specifically analyze DNA or chromosomes. In situ hybridization allows for the localization of specific DNA sequences within chromosomes or tissue sections. Karyotyping is a method used to visualize the complete set of chromosomes in an organism, which helps in identifying chromosomal abnormalities. DNA sequencing involves determining the precise order of nucleotides within a DNA molecule, providing insights into the genetic code.

Thus, disease phenotype analysis stands apart as it does not directly manipulate or assess the nucleic acid level, making it the appropriate selection for this question.